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Lotte Bjerre Knudsen: GLP-1 Receptor Agonists: Mechanisms, Translation, and Therapeutic Impact

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In this Assay Guidance Manual Webinar from May 6, 2026, Dr. Lotte Bjerre Knudsen discusses the history, chemistry, and biological mechanisms of GLP-1 receptor agonists, highlighting their evolution from early ideation to current therapeutic impact. Dr. Knudsen is an Honorary Professor in Translational Medicine at Aarhus University, Denmark. She is a former employee of Novo Nordisk, where she was last the Chief Scientific Advisor for Research & Development. A pioneer in GLP-1 based medicines, her contributions exemplify successful translational research, bridging basic discoveries to transformative therapies for metabolic and related diseases. Dr. Knudsen has received numerous awards for the work on GLP-1 medicines. Most recently, she was the recipient of the 2023 Paul Langerhans Award from the German Diabetes Association, the 2024 Science and American Association for Advancement of Science Mani L. Bhaumik Breakthrough of the Year Award (with Richard DiMarchi), the 2024 Lasker-DeBakey Clinical Medical Research Award (with Joel Habener and Svetlana Mojsov), and the 2025 Breakthrough Prize in Life Sciences (with Daniel Drucker, Joel Habener, Jens Juul Holst, and Svetlana Mojsov).

For more information about the Assay Guidance Manual eBook, workshops, and webinars, visit https://ncats.nih.gov/research/research-resources/agm
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semaglutide, obesity, fibrosis
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